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name the most important allosteric effector of glycolysis in the liverfructose-26-bisphosphate is the most important allosteric effector of
describe the nature of the enzymes involved in the phosphorylation of glucosephosphorylation of glucose glucose is converted to glucose-6-phosphate
name the three irreversible reactions in the glycolytic pathway the three irreversible reactions in the glycolytic pathway are
explain oxidative phosphorylation oxidative phosphorylation synthesis of atp from adp and pi during the passage of electrons in
define glycogenolysis glycogenolysis degradation of
explain electron transport chainelectron transport chaintransport of high-energy electrons through a series of carriers in
electron transport inhibitorsseveral compounds including specific drugs chemicals and antibiotics have been known to inhibit the
electron transport chainall processes require energy in living cells we constantly use energy for a number of biochemical reactions eg muscular
diabetes mellitmthis anabolic hormone exerts its action on key glycolytic enzymes thus leading to the conversion of glucose
explain glucocorticoids the adrenal cortex secretes the glucocorticoids which increase gluconeogenesis by increasing hepatic intake of amino
explain anterior pituitary gland secretes hormonesthe anterior pituitary gland secretes hormones that elevate the blood glucose and therefore
hyperglycaemic-in the fasting state glucose release from the liver increases due to the action of glucagon and in the muscle by epinephrine
glucokinasein the fed state clearance of blood glucose is mainly by liver via glucokinase glucokinase which is an inducible enzyme
regulation of blood glucose levelvarious levels of regulation are exerted at substrate level hormonal level enzymatic level and at organ level on
galactosemiainability of conversion of galactose to glucose results in the accumulation of galactose in the blood - known
explain glutathione peroxidaseglutathione peroxidase is a natural antioxidant present in many tissues together with vitamin e it is part of the
hmp shunt in erythrocyteshmp shunt in erythrocytes is of importance due to the generation of nadph which maintains the glutathione g-sh in
the fragility of erythrocytesthe fragility of erythrocytes is impaired in the absence of nadph generation due to the deficiency of
explain skeletal muscle skeletal muscle has low activity of glucose-6-phosphate dehydogenase yet like most other tissues it can synthesize
metabolic significance of hmp pathwayhaving gone through the hmp pathway you would have got some idea about the significance of this
regulation of hmp pathwaythe following factors play an important role in regulation of hmp pathwaya the first reaction of this pathway
explaintransketolase transketolase with the help of tpp and mg is required again this time it transfers carbon 12 from
the non-oxidative phase generates ribose precursorsthe non-oxidative phase of the pathway including the following reactions converts
1 the oxidative phase generates nadphthe oxidative branch of the pathway generates nadph and pentose-5-phosphate through the
metabolic reactions in the hmp pathwaythe hexose monophosphate pathway is responsible for the generation of a substantialfraction of the