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q define low - density lipoproteinansldl is the major cholesterol-rich lipoprotein carrying approximately 70 per cent of plasma cholesterol it serves
q define hepatic triglyceride synthesisfatty acid flux to the liver from adipose tissue appears to be an important determinant of hepatic
q define hepatic cholesterol synthesisthis is a highly complex process beginning with acetyl coa formed from fatty acid oxidation or from
triglyceride and cholesterol synthesized in the liver are secreted in very low density lipoprotein vldl particles which serve to transport the lipids
in the typical western diet approximately 80-140 g triglyceride and 05-15 g cholesterol are eaten daily following digestion absorption and
q define lipoprotein metabolismlipoproteins serve to transport absorbed dietary fat and endogenously synthesized cholesterol and triglyceride
q process of stabilize lipoprotein structureansapoproteins not only stabilize lipoprotein structure but also have other important regulatory
there are several different lipoprotein species found in plasma but their basic structures are similar the insoluble lipid cholesterol ester and
q define triglyceridestriglycerides are produced by the esterification of glycerol with three fatty acid molecules they are the bodys major energy
q what is cholesterolin its free unesterified form cholesterol is a major component together with phospolipid of cell membranes its presence helps to
q describe coronary spasmusually spasm develops at the site of subcritical or critical stenoses but it may also occur in angiographically normal
coronary vasoconstriction1 coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques with or without potential
1 the presence of epicardial coronary artery stenosis caused by artherosclerotic plaques is by far the most frequent angiographic finding in any
baroreceptor activity affects coronary vascular resistance reflexly with carotid occlusion baroreceptor hypotension leads to reflex adrenergic
q define neural and neurotransmitter controlcoronary arteries are richly innervated by adrenergic and parasympathetic nerves both alpha 1 and alpha 2
q what are diastolic compressive forcescoronary perfusion pressure equal to pressure gradient between the coronary arteries and the pressure in lv in
most of the coronary blood flow to the left ventricular myocardium occurs during diastole thus the contracting heart obstructs its own blood supply
the ability to maintain myocardial perfusion at constant levels in the face of changing driving presence is termed autoregulation in normal cases
endothelium is a source of vasoconstrictor factor also the best characterized of these are the endothelins endothelium produces only et1 unlike no
vasoactive substances such as endothelium derived relaxing factors edrf prostacyclin and endothelin can be formed in the vascular endothelium
q describe about coronary reactive hyperemiamyocardium depends almost completely on aerobic metabolism occlusion of a coronary artery even briefly
q can you define regulation of coronary blood flowduring diastole when the aortic valve av is closed aortic diastolic pressure is transmitted through
q can you explain relation between coronary artery and myocardial supplyansthere is a well-established relation between a given epicardial coronary
the epicardial coronary artery system consists of the left and right coronary arteries which normally arise from ostia located in the left and right
q define thrombospondin polymorphismsthrombospondin polymorphisms may present an initial insight into our understanding of the genetic contribution