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a the west of scotland coronary prevention study woscops the study randomized healthy men between the ages of 45 and 64 years with tc levels higher
q what is lipid-lowering trialaggressive lipid-lowering drug treatment of persons at various risk levels reduces coronary artery disease morbidity
a lipoproteins are large molecular compounds that are essential to the transport of cholesterol and triglycerides tgs within the blood they contain
dyslipidemia is an important correctable factor for coronary artery disease there is a strong independent continuous and graded relation between
q describe lipoproteinansthere is considerable current interest in this lipoprotein which consists of ldl with an additional apoprotein-apoprotein a
triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is
ldl is heterogeneous krauss and burke 1982 and can be separated on density gradient ultracentifugation into subclasses that vary in size density and
q what is reverse cholesterol transporthdl is involved in reverse cholesterol transport whereby cholesterol surplus to cellular requirements is
q define high density lipoproteins high density lipoproteins hdl are the smallest of the lipoprotein species and transport approximately 20 to 30 per
q what is low - density lipoprotein receptor pathwayansthe increasing cellular free cholesterol generated regulates the activities of two enzymes
q define low - density lipoproteinansldl is the major cholesterol-rich lipoprotein carrying approximately 70 per cent of plasma cholesterol it serves
q define hepatic triglyceride synthesisfatty acid flux to the liver from adipose tissue appears to be an important determinant of hepatic
q define hepatic cholesterol synthesisthis is a highly complex process beginning with acetyl coa formed from fatty acid oxidation or from
triglyceride and cholesterol synthesized in the liver are secreted in very low density lipoprotein vldl particles which serve to transport the lipids
in the typical western diet approximately 80-140 g triglyceride and 05-15 g cholesterol are eaten daily following digestion absorption and
q define lipoprotein metabolismlipoproteins serve to transport absorbed dietary fat and endogenously synthesized cholesterol and triglyceride
q process of stabilize lipoprotein structureansapoproteins not only stabilize lipoprotein structure but also have other important regulatory
there are several different lipoprotein species found in plasma but their basic structures are similar the insoluble lipid cholesterol ester and
q define triglyceridestriglycerides are produced by the esterification of glycerol with three fatty acid molecules they are the bodys major energy
q what is cholesterolin its free unesterified form cholesterol is a major component together with phospolipid of cell membranes its presence helps to
q describe coronary spasmusually spasm develops at the site of subcritical or critical stenoses but it may also occur in angiographically normal
coronary vasoconstriction1 coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques with or without potential
1 the presence of epicardial coronary artery stenosis caused by artherosclerotic plaques is by far the most frequent angiographic finding in any
baroreceptor activity affects coronary vascular resistance reflexly with carotid occlusion baroreceptor hypotension leads to reflex adrenergic
q define neural and neurotransmitter controlcoronary arteries are richly innervated by adrenergic and parasympathetic nerves both alpha 1 and alpha 2