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Question 1: Describe how appetite is regulated before and after a meal. Question 2: Describe the metabolic processes responsible for taking dietary fatty acids from a chylomicron in the bloodstream
Why is C.elegans a suitable model organism for studying the signalling pathways through which calorie restriction affects mammalian lifespan?
Question 1: Why is the liver described as the ‘hub' of lipoprotein metabolism? Question 2: Name a treatment for lowering cholesterol and explain its mechanism of action.
Give an example where a phosphatase can stop signal propagation through a receptor tyrosine kinaseinitiated intracellular signalling cascade. Provide two examples in which the signal of a GPCR&
Question 1: Name the three components of a membrane lipid. Question 2: Give an example for each of the above for a ganglioside.
Briefly describe three ways in which information from databases of protein amino-acid sequences can be used to infer potential functional interactions, giving the rationale for the inference in each
Discuss the challenges and promise of synthetic genomics: the whole genome engineering of novel biological organisms. Explain why modern beta-blockers work better than their first generation pred
Discuss the importance of structural plasticity and conformational changes in proteinprotein recognition. Illustrate with examples.
Describe how the formation of proteinprotein complexes can be controlled by (i) covalent modification, and (ii) the binding of small molecule ligands, including those designed for therapeutic i
Question 1: Explain what is meant by the term hydrophobic interactions. Question 2: Comment briefly on the contribution of i) hydrophobic interactions ii) hydrogen bonds to the affinity and spec
Give one piece of evidence that SpoIIQ and SpoIIIAH form a complex in vivo and one piece of evidence that they form a complex in vitro.
In muscle cells, a decrease in the amount of cytoplasmic calcium is associated with which of the following? A) Action potentials B) Muscle contraction mC) Muscle relaxation D) Rigor mortis
Describe a metabolic process demonstrated using the Enterotube or IMViC tests.
Which one of the following statements regarding the origin of metazoans has the most support? The choanoflagellates may share common ancestry with the Porifera. Metazoans are derived from many separ
Which of the following does not contain phospholipids in cell compartment? Endoplasmic reticulum, golgi apparatus, ribosomes, and lysosome.
Question 1: Before mid-blastual transition (MBT) , what events causes an embryonic cell to enter M phase and S phase? Question 2: What genetic processes do these events need in order to occur?
How does the hydrolysis of ATP(to ADP+P) after the proteins in a muscle cell to allow for contraction? A) Hydrolysis results in activation of myosin to the extended position B) Hydrolysis results in a
Partitioning in a sheet of cells is achieved by a)hemidesmosomes b)adherens junctions c)tight junctions d)desmosomes e)plasmodesmata
240.0mL buffer solution is 0.280M in acetic acid and 0.280M in sodium acetate. Question 1: What is the initial pH of this solution? Question 2: What is the pH after addition of 0.0050mol of HCl?
Question 1: Define the role of the cell wall in apoplastic movement. Question 2: How have Src mutations been particularly critical for understanding Src function and/or cancer?
Question 1: What can evolution explain about our moral and ethical beliefs and practices? What evidence do we have for particular evolutionary accounts of our moral and ethical beliefs and/or pract
How do van der waals and hydrophobic interactions affect the structure of double stranded RNA?
List some protein domains involved in protein to protein binding. Describe how the domains facilitates the binding. What other effects do the domains have?
Question 1: How will Src Protein Tyrosine Kinases Inhibitors be used? Explain the mechanism and outcomes Question 2: How do Francis Crick and James Watson's accounts differ? How do the differences i
Question: What is the targeting sequence for these proteins: A) Dopamine receptor B) Peroxidase