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list the requirements of implant materialsa biologically compatibility an ideal implant material will elicit mainly physiological reactions within
classify biomaterials and list some examplesbiologic classification is based on tissue response and systemic toxicity effects of the implant and is
define biomaterial and an implant and state their role in generalbiomaterial a pharmacologically inert material that is capable of interacting with
hydroxyapatite coatinghydroxyapatite coating has been recommended for clinical use these implants are superior with respect to the degree and rate of
what is metallic implantsmetallic implants undergo one or more several surface modifications to enable them to become suitable for implantation these
determine the biologic responsethe biologic response can includei metabolic disturbanceii inflammatory responseiii immune responseiv mutagenesisv
relation between tissue and the implant materialthe biologic interaction between the tissue and the implant material at an interface may result
what is machined implant machined implant has irregular surface roughness from approximately 10mum grooves and ridges in the machining direction the
implant surface affect osseointegrationsurface topography is critical as rough surfaces produce better bone fixation as compared with smooth surfaces
occlusal load affect osseointegrationthe timing and amount of overload are critical for osseointegration occlusal loading early where the primary
how bone density affect osseointegrationthe most important bone property is density which is influenced by factors such as patient age and genetics
how surgical technique affect osseointegrationthe osteotomy preparation is critical both from biologic and biomechanical points of view the bone
determine the biocompatibility of the material it is a vital factor as we have discussed in detail in the preceeding part of this unit the nature of
factors affecting osseointegrationa biocompatibility of the materialb surgical technique-c bone density -d occlusal loade infectionf implant
stages of contact osteogenesisosteoconduction this is the first and the most important healing phase and relies on the recruitment and migration of
contact osteogenesis in this the osteogenic cells attach to the implant surface and the new de novo bone is formed on the implant surface first the
explain the distant osteogenesisin this an extracellular matrix establishes the implant surface contact the osteogenic cells line the host bone
osteogenesisthe term osteogenesis describes essentially two distinctly different phenomena by which bone can become juxtaposed to an implant
mechanisms of endosseous integrationthree terms may be used to describe individual aspects of bone formation process that can occur around implants
molecular and cellular strategies to improve bone formation at implantsthe healing response of biological tissues to the oxide surface is sensitive
name the proteins used in oteoblastsome of these proteins include fibronectin thrombospondin osteopontin and osteoadherin most of them have rgd cell
what is osteoblastthe osteoblast is the key for the development of new bone it is essential that a large number of osteoblasts accumulate on the
essential concepts of endosseous healing1 osteoblast is the prime bone matrix synthesizing cell like most secretory cells osteoblasts are polarized
maturation and adaptation 18 to 54 weeksthe final stage involves maturation and adaptation of the implant-bone interface peri-implant bone and the
lamellar compaction and remodeling 6 to 18 weeksa remodeling phase is initiated in which hematopoietic-derived osteoclastic cells form cutting cones