Why is more heat is required to separate the strands


Discussion Post: DNA Sequences

• Which of the double-stranded DNA sequences below will require more heat to separate the two strands (select Option I or Option II)?

• Why is more heat is required to separate the strands?

Option I

5'-GGACTCCCGGGTGAG-3'
3'-CCTGAGGGCCCACTC-5'

Option II

5'-AACTGTTTAAAGACA-3'
3'-TTGACAAATTTCTGT-5'

• What will be the mRNA sequence that is produced during the transcription of the DNA sequence below? Hint: As we discussed in class, there is a slight difference in the nucleotides used in DNA vs RNA.

5'-ACGTCAGGTTTCCGT-3'

• Based on what was discussed in Lecture 9, name four enzymes/proteins that play a role in human DNA replication, and briefly describe the specific role each plays during human DNA replication.

The response should include a reference list. One-inch margins, Using Times New Roman 12 pnt font, double-space and APA style of writing and citations.

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