Problem: The Dutch Famine was an important natural experiment; its results have contributed to our understanding of nutrition and pregnancy outcomes.
A. Why is Dutch Famine a great example for studying the effects of maternal nutrition on pregnancy outcomes?
B. What is the conclusion from the Dutch Famine Study?
C. Please explain the concept of the fetal origin of metabolic disorders.
D. What could be the underlying molecular mechanism(s) that contribute to the fetal origin of metabolic disorders?