Problem:
The ability of the human body to catabolize ethanol in alcoholic beverages depends on the presence of alcohol dehydrogenase enzymes in liver cells. Ethanol intoxication leads to: (i) a dramatic decrease in NAD+ levels in liver cells, and (ii) a significant reduction in aerobic utilization of glucose.
Required:
Question 1: Why are NAD+ levels reduced by ethanol intoxication?
Question 2: Why is aerobic utilization of glucose (i.e. TCA Cycle activity) reduced by ethanol intoxication?
Does anyone know how to go about this search to explain it.