1. The reasons why Jeremiah was apparently healthy during the first 5 months in his life.
2. The reasons why both B and T cell counts low but NK cell numbers normal?
3. How did the phagocytosis, respiratory burst and lysozyme assays help to diagnose this disease.
4. How does Jeremiah's family history help understand the genetics of this disease?
5. Which immunological process is impaired in Jeremiah? Which is the gene/s that could be implicated in this deficiency?
6. What assay would you perform in the lab to identify the enzymatic deficiency?
7. If Jeremiah breaks a bone later on in his life, would you advice his parents to get X-rays of the fracture bones or not?
8. Why is Jeremiah's condition associated with skin manifestation such as lack of hair?
9. Suggest possible therapies for this condition.