When repeat syphilis serologic evaluation be performed


Assignment task:

A 27-year-old transgender woman presents with a 2-day history of a diffuse rash, most prominent on her chest and back. She reports having receptive anal sex with several cisgender men in the last 2 months. Physical examination shows an erythematous macular rash on her chest, back, and palms. She has no visual, hearing, or neurologic complaints, and a neurologic examination is normal. A clinical diagnosis of secondary syphilis is made. Laboratory studies are ordered, and she is treated with a single intramuscular dose of 2.4 million units of benzathine penicillin G. Later, the laboratory studies return with a positive treponemal enzyme immunoassay (EIA), a Rapid Plasma Reagin (RPR) titer of 1:256, and a negative HIV-1/2 antigen-antibody test. When should repeat syphilis serologic evaluation be performed? No follow-up is needed since appropriate treatment was administered 6 and 12 weeks 6 and 12 months 12 and 24 months

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