Question: You have a patient whom you determine is having a little trouble with depression. She is a 37 year-old female who is in the midst of a divorce after 15 years of marriage. Although part of her depression is secondary to her marital troubles, she admits that she has had symptoms of depression (lack of energy, disinterest in her normal activities, hypersomnia) long before the divorce proceedings began. She is not suicidal and refuses to see a psychiatrist or therapist for counseling. You determine her to be in good health. She has no medication allergies, no other medical conditions, and the only medications she currently takes include a multivitamin and birth control pills. Which of the following would represent the most rational therapy? 1) Quetiapine (Seroquel®) 2) Citalopram (Celexa®) 3) Amitriptyline (Vanatrip®) 4) Lithium (Lithobid®)