Problem
HT is a 31 year old female with acute, uncomplicated cystitis and no known drug allergies. She has no significant PMH or medications. Her urine culture shows a susceptible E. coli (susceptible to all treatments listed below). What would cause you to choose one option over another?
i. Nitrofurantoin 100 mg po BID x 7 days
ii. TMP/SMX DS (160 mg/800 mg) po BID x 3 days
iii. Levofloxacin 250 mg po daily x 3 days
iv. Cephalexin 500 mg po q12hrs x 7-14 days.