Question: When preparing for discharge, which teaching about glargine insulin would be most appropriate? When preparing for discharge, which teaching about glargine insulin would be most appropriate? You should take this medication every morning. Use caution with beta blockers that mask the signs and symptoms of hypoglycemia. You should mix this insulin with your regular insulin to reduce the amount of injections that must be given. This medication can cause irritation at the injection site and should be monitored for infection.