Problem
You are recording mm from a neuron in a brain slice taken from a day 5 old mouse. When you electrically stimulate synaptic transmission in the presence of CNQX and APV, you obserye action potentials.
1. Why might this be this surprising (or non-intuitive to non-experts)?
2. Given your new-Found understanding of developmental neurobiology, what neurotransmitter do you think is responsible for your observation? Explain your answer in terms of ions and membrane proteins.
3. How would the response to stimulation be different in tissue from a 20 day old animal? What molecular processes underlie this change?