Problem
i. What makes a tissue responsive to a hormone?
ii. Who first demonstrated that the testes are responsible for the development of secondary sexual characteristics in males?
iii. What is the enzyme synthesized during the darkness that is the rate-limiting step for melatonin synthesis?
iv. What happens when a ligand binds the tyrosine kinase receptor hormone binding domain?
v. Where would you find a hormone-binding globulin? (i.e., what tissue or fluid)
vi. What causes the LH surge during the ovulation period of the human menstrual cycle?
vii. testosterone and estradiol are ONLY made in the gonads . True/false
viii. Type 1 steroid hormone receptors form a heterodimer before binding to the hormone response element on DNA
ix. Males and females are sexually dimorphic in their GnRH-ir cell expression response to estradiol treatment.True/false
x. Males demonstrated a significant decrease in GnRH-ir cells, as compared to controls, when treated with estradiol . True or False?