What is the result of the active nf-kb pathway which, Chemical Engineering

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What is the result of the active nf-kb pathway which

The NF-kB signal pathway is active in inflammation. Several models of the pathway have been developed (Hoffmann et al., 2002; Lipniacki et al., 2004). What are the important proteins that are active in the pathway? How is the pathway controlled? Is there feedback in the pathway? What is the result of the active NF-kB pathway? Which diseases are attributed to the NF-kB pathway?

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