What is the reaction of enzyme and substrate


Propblem:

Question: Suppose I'm using 200 nmoles of enzyme and 2 mmoles of substrate. The enzyme should be saturated but if I use 50 mmoles of substrate, the reaction will be faster.

Why? I just can't get it! Even at lower concentration of substrate the enzyme is saturated (all enzyme molecules are engaged in the reaction) but still the reaction rate is lower.

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Biology: What is the reaction of enzyme and substrate
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