Problem:
Citrate synthase catalyzes an aldo - type condensation. the kinetic mechanism is a random-sequential one where either substrate can bind first. Based on this calue for the free energy change for hydrolysis of citryl-coA and that of the citrate synthase reaction ( -32 KJ/mol),
Required:
Question: What is the G' for the formation of citryl coA from OAA and AcCoA?
Any help would be greatly appreciated!