What is single point mutation in genomic dna

Question

Problem:

Question: which of the following is true regarding single point mutation in genomic DNA sequence:

1. Changes in dna sequence will always go in the amino acid change in the primary sequence
2. Single nucleotide changes in DNA will have no changes in the primary sequence of protein
3. Single mutation will always introduce a frame shift
4. Single mutation will always introduce a nonzeftone mutation

Give reasoning with your answer.