What is Act on incretin hormone to indirectly effect insulin production
Monotherapy and Combination Therapy
Sitagliptin (Januvia) and Saxagliptin (Onglyza)
Well tolerated, low risk for hypoglycemia, do not cause weight gain
Caution with renal impairment
Need serum Cr and CCr prior to admin
Pregnancy Category B, need to be using insulin; Do not use in breastfeeding