What is a transcriptome and what is an orfeome
Problem
What is a transcriptome? What is an ORFeome? Are they the same? How would you map which parts of a fully sequenced genome are expressed?
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Can you complement a dominant mutation? Why or why not? What would tip you off that the mutation you've isolated is dominant and how would you check?
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What sample would you request for a confirmatory test and why? What is the predicted karyotype ISCN diagnosis of the fetus based on FISH analysis?
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