Problem: What should patients do if they change their minds about the instructions stated in an advance directive? Need Assignment Help? Click the correct answer and click Submit. . Tell the physician or other healthcare team member about the changes and complete a new advance directive form. There is no need to inform anyone of the changes until the medical situation warrants it. Change their current advance directive on their own and put it in a secure place. Patients cannot make changes to their advance directives after being admitted to the hospital.