Question: What is the initial treatment for uncomplicated anterior epistaxis? What is the initial treatment for uncomplicated anterior epistaxis? Want Professional Help? Tilting the head back so the blood does not run out of the nose Applying firm and continuous pressure superior to the nasal alar cartilages for 10 to 15 minutes Applying firm and continuous pressure to the nostril for 5 minutes Letting the nose bleed clot and leaning the head forward