Problem
Summarize the CIOMS guidance documents in your thread. If your thread contains more than one CIOMS guidance document - how has CIOMS' position changed over time? Summarize the literature that cites (includes as a reference) the CIOMS guidance documents in your chosen thread. What impact has the CIOMS guidance documents had on international drug and device development? Quantify the literature - how many times has your CIOMS document(s) been cited? What other international entities have had an impact on the topic (e.g. U.S. FDA, EU EMA, etc.)? Summarize the literature that cites (includes as a reference) the literature that directly cites the CIOMS document (if applicable). If no literature directly cites the CIOMS document, summarize the literature related to the topic(s) covered by the CIOMS document(s) in your chose thread.