Problem
Antistreptolysin O (ASO) titer
• What is meant by titer? How is this derived at?
• Why is it abnormal for an individual to have chronic increased ASO titer?
• What are the consequent pathologic conditions in chronic streptococcal infection? Why do they happen?
• What immunologic processes are involved in these consequences?
• Should a qualitative method be found positive, how can one determine the ASO titer?