What enzymes catalyzes the interconversion of Fructose-6-phophate and Fructose-2,6-Bisphosphate? What is unusual about these enzymes?
How does a cell determine which of the two enzymes referenced in above Question will be active?
Predict how insulin and glucagon affect PFK2/FBPase
Does glucagon trigger phosphorylation of the serine residue or dephosphorylation? Insulin? How do you know?
If the liver were resistant to insulin, what would happen to glycolysis and gluconeogenesis?
Fructose metabolism is not regulated by ATP and is independent of insulin.
What if high-fructose feeding also makes the liver insulin resistant? What would we see?