What does the change from mona to thrombin2 involve, Other Subject

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What does the change from mona to thrombin2 involve

Problem 1: What does the change from MONA to THROMBIN2 involve? That is, what is the difference between the two protocols? (Please cite an authoritative resource to support response)

Problem 2: What is the rationale for the change from MONA to THROMBIN2? (Please cite an authoritative resource to support response.)

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Other Subject: What does the change from mona to thrombin2 involve

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