What depth penetration one get with atomic force microscopes


Problem:

What depth penetration can one typically get with atomic force microscopes? (i.e. how far into the tissue can one image?). I have found numbers on acquisition times (minutes) and spatial resolutions (~nm), but what about depth?

Also, what is the sensitivity of AFM? (e.g. in moles) Explain in detail.

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Biology: What depth penetration one get with atomic force microscopes
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