Question: Which of the following best explains the pathophysiological mechanisms that contribute to dyspnoea in asthma? Question options: a) Release of inflammatory mediators cause airway hyper-responsiveness, which causes bronchoconstriction and airflow limitation b) Bronchodilation causes increased airflow into alveoli and therefore causes gas-trapping c) Mast cells degranulate causing vasoconstriction of airway vasculature, decreasing gas exchange d) Impaired mucociliary clearance and increased mucus viscosity