Assignment Task:
Joanna Hernandez is a 75 year old female who presents to your office with a chief complaint of swollen and aching gums. A thorough examination reveals an infection around one of her molars which will require antibiotic treatment. Other than the infection, detailed medication/health history reveals a healthy 110 pound female whose only medications are hydrochlorothiazide 25 mg every morning for her high blood pressure and acetaminophen for aches and pains. Mrs. Hernandez is quite proud of the fact that she still has her own teeth. However, she is not happy that she has this infection. Ms. Hernandez also requests something for the pain. You then refer to Ms. Hernandez's dental record and see that she is allergic to penicillin and to ibuprofen.
1. Though Mrs. Hernandez appears healthy and weighs 110 pounds what are your concerns regarding drug distribution
2. Mrs. Hernandez takes hydrochlorothiazide and acetaminophen as oral tablets. What are the advantages and disadvantages of oral administration of drugs
3. How could Mrs. Hernandez's infection affect the absorption of a locally administered (parenteral) drug? Need Assignment Help?
4. What are some of the different factors that may affect drug absorption in Mrs. Hernandez?
5. Mrs. Hernandez tells you that her friend recommended that she take St. John's wart for some "depression." What can you tell me about St. John's wart. Include adverse effects and drug interactions.