What are the intracellular changes caused by morphine
Problem: What are the intracellular changes caused by morphine binding to its therapeutic 'on-target' receptor?
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Question: What is the mechanism of the therapeutic effects of morphine?
Problem: Does morphine cause an increase or decrease in free intracellular calcium?
Question: Does morphine primarily bind to its therapeutic 'on-target' receptor at the brain or spinal cord?
Question: Which is the therapeutic on-target receptor for morphine; MOR or mu, or are they the same?
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