Problem
You discover a new strain of mice on a small island off the coast of Australia, with oval- shaped eyes (determined by the oe- allele) and long legs (determined by the 11+ allele). This is unlike your lab mice with round eyes (determined by the oe+ allele) and short legs (determined by the 11+ allele). You determine the Australian alleles are hypomorphic mutations in the genes that regulate eye shape and leg length and that the lab alleles produce functional proteins (meaning there are no mutations) from both of these genes. You know that the eye shape and leg length genes are linked and have 8cM between them.
1. You cross an Australian mouse to a lab mouse. What are the genotypes, phenotypes, and frequency of the offspring from this cross?
2. You take an offspring from the cross and cross it to an Australian mouse. What are the genotypes of the offspring?
3. You take an offspring from the cross in question and cross it to an Australian mouse. What are the phenotypes of the offspring? Indicate the parental and recombinant phenotypes and the frequencies.
4. Your co-worker wants to replicate your cross, however, his 50% Australian/50% lab mouse has the trans orientation of alleles. Are the parental and recombinant gametes produced by your co-workers mouse the same or different from yours and if different what are they?