What are the different mechanisms responsible for corneal avascularity?
Various mechanisms responsible for its avascularity are as follows:
a) Chemical Theory:
I) Role of VIF: thought to be sulfate ester of hyaluronic acid. Presence of this substance has been postulated, as a reason for corneal avascularity.
2) Role of VSF: thought to be an LMW amine. This substance has been demonstrated to the present at the site of lesion.
b) Mechanical Theory
The blood vessel is said to be stopped from growing into the cornea because of its compact nature.
c) Combination of mechanical and chemical theories has been thought as the cause of transparency lately.
d) Role of Leukocytes
These inflammatoly substances has essential role in stimulating corneal vascular growth.