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What are the common models of absorption across membranes

What are: the Common Models of Absorption across Membranes and Transport to Target Sites and the Major Modes/Pathways for Biotransformation and Elimination and for the chemical for the following chemicals with giving one example of a Mechanism of Toxicity at the Major Target Site:

1- Lead (inorganic)

2- Toluene

3- Methyl ethyl ketone (MEK)

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Biology: What are the common models of absorption across membranes

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