What are the chances her mother was a carrier what are the

Question

Assignment: Genetics Lab

Patient Bios

Kayla Age: 35 Kayla is seeking genetic counseling for muscular dystrophy.

Emily Age: 40 Emily is seeking karyotype analysis

Patient Chart

Please use the below chart for navigation to the tests.

Kayla	Emily
Scenario 1 - Pedigree Analysis (Page 2)	Scenario 2 - Karyotype (Look on Page 5)

Relationship between 1 and 2	Gender of Fetus
Relationship between 1 and 5	Chromosomal Abnormalites
Relationship between 1 and 10	Chromosomal Combination Result
Relationship between 6 and 7
Relationship between 4 and 5
Relationship between 5 and 8
Relationship between 8 and 10
Relationship between 1 and 3
Chances mother is a carrier
Chances Kayla is a carrier
Chances Kayla passes the syndrome to male child
If Kayla is a carrier, what are chances of having an affected child?
If Kayla is not a carrier, what are chances of having an affected child?

Kayla has a family history of Duchenne muscular dystrophy (DMD), which is a sex-linked trait. The patient wishes to know her risk of having an affected child. Her grandmother was a known carrier. DMD is an inherited disorder that involves progressive muscle weakness. It affects approximately 1 in 3500 male births worldwide and is inherited in an X-linked recessive pattern.

The following pedigree was drawn up by the genetic counselor. Our patient, Kayla, is #13.

What are the relationships between:

1 and 2 ________________ 1 and 5________________
1 and 10 ________________ 6 and 7_________________
4 and 5 __________________ 5 and 8_________________
8 and 10_______________ 1 and 3__________________

What are the chances her mother was a carrier?

What are the chances our patient is a carrier?

What are the chances she passes the syndrome to a male child?

Testing would establish her status as either a carrier or a noncarrier.

If she is a carrier what are the chance of her having an affected child?

If she is not a carrier what are the chance of her having an affected child?