Dr. Osterholm has cited that in our last century alone, approximately 500 million people died of smallpox. This compares with 320 million deaths during the same period from all deaths due to wars, cases of the 1918 flu epidemic, and all cases of AIDS worldwide. Are vaccines a viable strategy, perhaps in some cases but not all cases? Do you want to be vaccinated with the smallpox vaccine? Tell us why or why not.