The MN blood group in humans is under the control of a pair of codominant alleles, LM and LN. In a group of 556 individuals, the following genotypic frequencies are found:
167 MM
280 MN
109 NN
(a) Calculate the frequency of the LM and LN alleles.
(b) Test (using the Chi-squared test) whether the genotype frequencies conform to the Hardy-Weinberg distribution.
Genotypes
MM MN NN Sum
Observed number
Observed frequency
Expect frequency
Expected number
(O-E)2/E