The following plasma concentrations (in ug/ml) of a new drug were recorded in a patient. Is this data best fit by a single or double compartment model?
Time (hr) conc.
0.26 0.6149
0.51 0.4299
0.77 0.3213
1.02 0.2203
1.25 0.1773
1.51 0.1242
1.76 0.1167
2.02 0.0928
2.25 0.0722
2.51 0.0658
2.76 0.0614
3.02 0.0607
4.02 0.0471
5.01 0.0505
6.01 0.0438
7.01 0.0379
8.01 0.0325
9 0. 0305
10 0 .0282
From my understanding, you just need to either do a single exponential fit or a more complex exponential fit to see which fits the points better and determine single vs. double compartment model.