Question: Which of the following statements regarding the management of post-traumatic stress disorder (PTSD) is FALSE? SSRIs and other drugs are most effective in improving hyperarousal and mood. TCAs and MAOIs are used as second-line agents Prazosin should be started with a dose of 3-15 mg to increase its efficacy. An SSRI should be started at its lowest dose and gradually titrated. Early treatment may prevent chronicity.