Severe deformities of the skeletal system


When rabbits with the Pelger anomaly were mated to each other, Nachtsheim found 223 normal progeny, 439 showing the Pelger anomaly, and 39 extremely abnormal progeny.

These very abnormal progeny not only had defective white blood cells, but also showed severe deformities of the skeletal system; almost all of them died soon after birth. In genetic terms, what do you suppose these extremely defective rabbits represented? Why do you suppose there were only 39 of them? 

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Other Subject: Severe deformities of the skeletal system
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