Problem: An internist calls you to ask about selecting a selective serotonin reuptake inhibitor (SSRI) for a patient of hers who is depressed. She tells you that the patient has never been treated with an antidepressant before, is taking no other medications, and has no serious medical problems. Which of the following is true? Need Assignment Help? A. The SSRIs have a narrow therapeutic index. B. Paroxetine (Paxil) has significant anticholinergic activity at higher dosages. C. The metabolites of citalopram have significant pharmacologic activity.