Rotenone, antimycin A and cyanide are poisons that inhibit the electron flow through respiratory chain. Rotenone inhibits the electron flow through NADH-Q oxireductase. Antimycin A blocks electron flow between cytochrome b and c1. Cyanide blocks electron flow though cytochrome oxidase to O2.
Predict the relative oxidation-reduction state of each of the following respiratory chain components that are treated with each of the inhibitors.
(a)NAD+
(b)NADH-Q oxireductase
(c) coenzyme Q,
(d) cytochrome c,
(e) cytochrome a.