Problem: During the period of time from 1999 to 2014, what was the relationship between opioid prescriptions and opioid overdose deaths?
1. As opioid prescriptions decreased, the number of opioid overdose deaths actually increased.
2. As opioid prescriptions increased, the number of opioid overdose deaths actually decreased.
3. Both prescriptions of opioids and opioid deaths decreased dramatically.
4. Both prescriptions of opioids and opioid deaths increased dramatically.