Write a Brief report on the topic :"Protein Phosphatase"
Introduction:-Protein phosphorylation constitutes to one of the major types of reversible post transnational modifications that can regulate the stability, localisation or the function of a particular protein. Hydroxyl group containing amino acids such as Ser, Thr & Tyr are the sites of phosphorylation in proteins (approximately 86%, 12% and 8% of the phosphoproteome respectively). Phosphorylation at these amino acid residues is catalysed by a specific group of enzymes known as "PROTEIN KINASES".
Address the following points given below:
- Introduction
- Classification of protein phosphates
- Structure and mechanism of action
- Physiological significance of phosphate function
- Laboratory methods to study protein phosphorylation/dephosphorylation
- Disease relevance and therapeutic significance
- Obstacles in analysing phosphate function
- Future directions
- References
Academic requirements:
• Your work must be submitted as 2600 words.
• Your work should be submitted in the formats outlined for each point in the assignment
• The entire assignment brief and completed .
• All work must be referenced using the Harvard /APA method.
• Provide a reference list