Question: Adult patient presents with a sudden onset of severe pain, redness, and swelling in the right big toe. Laboratory analysis shows an elevated uric acid level. Which underlying pathophysiologic mechanism is primarily responsible for this patient's presentation? • Formation of monosodium urate crystals leading to neutrophil activation • Deposition of calcium pyrophosphate dihydrate crystals in the synovium • Immune complex deposition in the synovial lining of the joint • Accumulation of cholesterol crystals within the synovial fluid