Assignment task:
A 27-year-old man presents for follow-up of a positive syphilis serologic test result. Recent laboratory studies from a routine visit 8 days ago show a positive treponemal enzyme immunoassay (EIA) and a positive Rapid Plasma Reagin (RPR) with a titer of 1:256. He had a negative HIV-1/2 antigen-antibody test and is taking tenofovir DF-emtricitabine for HIV preexposure prophylaxis (PrEP). He had testing for sexually transmitted infections, including syphilis, 3 months ago and these tests were all negative. He returns to receive treatment for syphilis. He denies any genital ulcers or skin manifestations, but he reports blurry vision in the right eye during the past 4 days. A diagnosis of ocular syphilis is suspected. Which one of the following statements about ocular syphilis is TRUE? All persons with ocular syphilis require a lumbar puncture with cerebrospinal fluid analysis, regardless of neurologic symptoms Uveitis is the most common manifestation of ocular syphilis Corneal lesions are the most common manifestation of ocular syphilis The treatment of ocular syphilis is the same as the treatment for late latent syphilis