Assignment task:
Construct a 5- to 6-page paper discussing each of the four traditional mood stabilizer medications: carbamazepine, lamotrigine, lithium, and valproate products. Support your answers with five (5) evidence-based, peer-reviewed scholarly literatures.
Note: APA style format will apply.
Your paper should include the following for each:
1. Proposed mechanism of action
2. Baseline assessment, laboratory considerations, and frequency of ongoing labs and assessments
Note: Discuss the importance of assessment and labs.
3. Special population considerations (birth assigned gender, age, other medical comorbidity considerations)
4. FDA approval indications
5. Typical dosing with discussion on therapeutic endpoints for psychiatric use
6. Major drug-drug interaction considerations
- For each of these medications, please review potential drug-drug interactions listed below. Consider alternative dosing schedules, clinical implications for the drug interactions, additional patient education needed, any additional monitoring recommended, or collaboration needed with other medical professions (such as, primary care providers)
- Lamotrigine + Valproate
- Lamotrigine + Rifampin
- Valproate + Estrogen containing birth control.
- Valproate + Amitriptyline
- Lithium + Furosemide
- Lithium + Lisinopril
- Carbamazepine + Lurasidone
- Carbamazepine + Grapefruit juice
- Discuss the ethical, legal, and social implications related to prescribing bipolar and other related mood-disorder diagnoses therapy for patients.
Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. For this Assignment, you are only required to include a title page. The Walden Writing Center Sample Paper provides an example of those required elements.
Be sure to separate your paper into sections based on each of the question prompts you are being asked to answer. For example:
Mechanism of Action:
- Carbamazepine
- Valproate
- Lithium
- Lamotrigine
Baseline assessment, laboratory considerations, and frequency of ongoing labs and assessments:
- Carbamazepine
- Valproate
- Lithium
- Lamotrigine
Special population considerations (birth assigned gender, age, other medical comorbidity considerations):
- Carbamazepine
- Valproate
- Lithium
- Lamotrigine
FDA Approved Indications:
- Carbamazepine
- Valproate
- Lithium
- Lamotrigine
Typical dosing with discussion on therapeutic endpoints for psychiatric use:
- Carbamazepine
- Valproate
- Lithium
- Lamotrigine