Problem: A nurse is teaching a newly licensed nurse about preventing infections in a client who has a peripheral inserted central catheter (PICC). Which of the following information should the nurse include in the teaching? Want Professional Help? Clean the hub of the PICC line with an alcohol wipe for 5 seconds prior to an injection. Change gauze dressing over the PICC line every 72 hr. Change intermittent intravenous tubing every 24 hr. Replace IV fluids after the bag has hung for 36 hr.