Problem: The nurse is preparing to administer the antianginal drug nitroglycerin to a patient. The nurse knows which of the following are correct? Select all that apply. Long-acting preparations do not need to be tapered. May produce severe headache Effects of sublingual nitroglycerin begin rapidly-in 10 to 15 minutes Causes orthostatic hypotension - administer sitting or lying Acts directly on vascular smooth muscle to promote vasodilation