Data are collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against a placebo. After treatment for 5 days with the new compound or placebo, the extent of wound healing is measured and the data are shown in Table 6-25. Suppose that clinicians feel that if the percent reduction in the size of the wound is greater than 50%, then the treatment is a success.
A. Generate a 95% CI for the percent success in patients receiving the new compound.
B. Generate a 95% CI for the difference in the percent success between the new compound and placebo.
C. Generate a 95% CI for the RR of treatment success between treatments.
D. Generate a 95% CI for the OR of treatment success between treatments.
Table 6-25
New Compound None=4, 1-25= 11, 26-50= 11, 26-50= 37, 51-75= 32, 76-100= 41
(n=125)
Placebo None=12, 1-25= 24, 26-50= 45, 51-75= 34, 76-100= 10
(n=125)