Body fluids were examined from patients with a Chondrosarcoma over the time initial treatment and remission. The levels of a particular chemotherapeutic drug were followed over a selected week. The Nadir or minimum level was selected for analysis. The trial continued over an 8 week period. Using each week's nadir, the pattern looks like:
| Subject |
NADIR1 |
NADIR2 |
NADIR3 |
NADIR4 |
NADIR5 |
NADIR6 |
NADIR7 |
NADIR8 |
ALLNADR |
| 1 |
13.2 |
13 |
13 |
13 |
13.6 |
14.1 |
14 |
14 |
13 |
| 2 |
11.2 |
11.2 |
11.4 |
11.9 |
11.8 |
12 |
12 |
13.8 |
11.2 |
| 3 |
10.2 |
10.4 |
10.7 |
11 |
11 |
11.2 |
11.1 |
11.8 |
10.2 |
| 4 |
11.1 |
11 |
9.2 |
8.7 |
9.3 |
10.3 |
9.7 |
10.1 |
8.7 |
| 5 |
12.7 |
12 |
11.9 |
11.4 |
10.3 |
11 |
9.7 |
7.5 |
7.5 |
| 6 |
12 |
12.5 |
11 |
11 |
11 |
10.4 |
10.2 |
11.6 |
10.2 |
| 7 |
12.7 |
12.4 |
12.1 |
11.5 |
11.3 |
10.4 |
11 |
0 |
10.4 |
| 8 |
9.3 |
10.4 |
10.6 |
10.5 |
11 |
10.9 |
11.1 |
10.4 |
9.3 |
| 9 |
12.9 |
12.5 |
12.4 |
12.2 |
12.1 |
12.9 |
11.8 |
11.5 |
11.5 |
| 10 |
12.8 |
13.4 |
10.8 |
10.3 |
10.7 |
10.2 |
10.8 |
11.5 |
10.2 |
| 11 |
11.6 |
11 |
10.1 |
10.3 |
10.9 |
7.8 |
8.2 |
9.2 |
7.8 |
| 12 |
10.8 |
11 |
10 |
11.2 |
11 |
9.8 |
7.7 |
9.6 |
7.7 |
| 13 |
11.2 |
11.4 |
11.8 |
11.3 |
9.9 |
10.6 |
11.3 |
11.6 |
9.9 |
| 14 |
14.2 |
12.4 |
12.2 |
10.6 |
10.6 |
10.9 |
10.4 |
11.2 |
10.4 |
| 15 |
10.8 |
9.3 |
10.4 |
10.7 |
10.4 |
10.8 |
11 |
11.6 |
9.3 |
| 16 |
12.3 |
12.6 |
11.9 |
11.8 |
12.8 |
12 |
11 |
11.4 |
11 |
| 17 |
12.4 |
12.6 |
12.4 |
12.9 |
12 |
11.6 |
11.5 |
10.9 |
10.9 |
| 18 |
11.1 |
11.6 |
10.8 |
10.8 |
10.8 |
10.5 |
10.7 |
10.2 |
10.2 |
| 19 |
12.4 |
12 |
11.8 |
12.9 |
11.3 |
11.4 |
12 |
12.5 |
11.3 |
| 20 |
11.4 |
11.4 |
11.4 |
10.8 |
10.7 |
11.2 |
11.4 |
10.5 |
10.5 |
| 21 |
11.2 |
10.7 |
10.3 |
9.5 |
10.1 |
9.8 |
9.8 |
10.5 |
9.5 |
| 22 |
11.2 |
9.8 |
8.7 |
9.3 |
8.6 |
8.9 |
9.2 |
8.4 |
8.4 |
| 23 |
12.6 |
12.6 |
12.5 |
12.3 |
12.1 |
12 |
11.3 |
12 |
11.3 |
| 24 |
11.1 |
11.5 |
11.6 |
11.6 |
10.5 |
11.6 |
11.2 |
10.5 |
10.5 |
| 25 |
12 |
11 |
10.5 |
11 |
11.2 |
11.1 |
10.6 |
9.4 |
9.4 |
| 26 |
11.7 |
10.5 |
12.1 |
10.7 |
10.1 |
8.9 |
11.5 |
12 |
8.9 |
| 27 |
11 |
12.1 |
12.7 |
11 |
12.4 |
11 |
11.8 |
12.5 |
11 |
| 28 |
12.5 |
11.7 |
12 |
11 |
12.4 |
12.1 |
12 |
12.3 |
11 |
| 29 |
8.2 |
8.2 |
9.4 |
10.5 |
10.1 |
9.6 |
9.5 |
9.6 |
8.2 |
| 30 |
12.7 |
12.1 |
12.3 |
11.4 |
11.2 |
12.4 |
11.4 |
10.8 |
10.8
|
Are there any difference in the weeks? Is there a trend over time? This is a paired question and requires Tukey HSD for proof.
Using statisical analysis software to proof.